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This tool is supported wholly or in part by The Human Brain Project.

This tool supports NIfTI-1.

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Research Imaging Institute, UTHSC San Antonio
Mango is a multi-platform Java based image processing application developed for use in the Neuroimaging community. Processing tools are provided for MRI, CT, PET and SPECT images. Mango supports common image types (NIFTI, Analyze, DICOM, ACR-NEMA) and provides import capability for practically any biomedical image format (2-, 3-D and 4-D). Extensive entering and editing tools provide means to define ROIs and copy them between images using image or world coordinates, simplifying copying between low and high resolution images. It supports up to eight true image overlays (in image or world mode), with independent control of display window settings and colors. Analysis tools are provided for histogram generation, statistics (image or ROI based), interactive affine transforms, as well as 3-D surface generation and display. See the Mango website ( for videos demonstrating many of the image processing and display features.
NIfTI-1 support
Full i/o support is provided for NifTI-1.
Jack L. Lancaster & Michael J. Martinez
freely distributed
How to get
Available at the Mango website (
Current version
Release 2.3.2
Current version release date
Open source
educational, scientific, and non-comercial use
Available free of charge
Mango requires Java JRE Version 5.0 or greater to use.
Technical publications

Image-Based Analysis of Fundamental Features of Brain Structures. Jack L. Lancaster, D. Reese McKay, Matthew D. Cykowski, Michael J. Martinez, Xi Tan, Sunil Valaparla, Yi Zhang, Peter T. Fox. Neuroinformatics, Accepted for pub Feb 2011. (Mango used extensively for analysis and to make Figures 2, 3 & 5).

Anatomical global spatial normalization. Lancaster JL, Cykowski MD, McKay DR, Kochunov PV, Fox PT, Rogers W, Toga AW, Zilles K, Amunts K, Mazziotta J. Neuroinformatics, 2010 Oct;8(3):171-82 (Mango used in processing and to make Figures 1, 2 & 4).

Applications publications

Metaanalytic connectivity modeling: delineating the functional connectivity of the human amygdala. Robinson JL, Laird AR, Glahn DC, Lovallo WR, Fox PT. Hum Brain Mapp, 2010 Feb;31(2):173-84. (Mango used in processing and to make Figures 1 & 3).

Modeling motor connectivity using TMS/PET and structural equation modeling. Laird AR, Robbins JM, Li K, Price LR, Cykowski MD, Narayana S, Laird RW, Franklin C, Fox PT. Neuroimage, 2008 Jun;41(2):424-36. Epub 2008 Feb 15. (Mango used in processing and to make Figures 1 & 2).

Other information
atlas, functional, HBP supported, NIfTI-1 support, registration, segmentation, surface analysis, Talairach Daemon, multiple ROIs, multiple overlay, visualization, volume
Java, Linux, MacOS, UNIX, Windows
IATR listing last updated
10 Feb 2011