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RAVENS (Regional volumetric analysis of brain images)
Performs elastic spatial normalization of brain images, in a mass-preserving framework, which allows for volumetric measurements of very high spatial resolution and with no apriori definitions of ROIs.
NIfTI-1 support
Dinggang Shen, Christos Davatzikos
Christos Davatzikos at
How to get
Contact Christos Davatzikos at
Current version
Current version release date
Open source
Available free of charge
Unix or Linux
Technical publications
1. D. Shen and C. Davatzikos, “Very High Resolution Morphometry Using Mass-Preserving Deformations and HAMMER Elastic Registration”, NeuroImage, 18(1):28-41, January 2003.

2. C. Davatzikos, A. Genc, D. Xu, and S.M. Resnick, “Voxel-Based Morphometry Using the RAVENS Maps: Methods and Validation Using Simulated Longitudinal Atrophy”, NeuroImage, 14:1361-1369, December 2001

3. C. Davatzikos, H. Lee, E. Herskovits and S.M. Resnick, ``Analysis of accuracy and sensitivity in detecting brain activations via statistical parametric mapping: A study using a PET simulator'', NeuroImage, 13:176-184, 2001.

4. C. Davatzikos, ``Measuring biological shape using geometry-based shape transformations'', J. Image and Vision Comp., 19:63-74, 2001.

5. A.F. Goldszal, C. Davatzikos, D.L. Pham, M.X.H. Yan, R.N. Bryan, and S.M. Resnick, ``An Image Processing Protocol for Qualitative and Quantitative Volumetric Analysis of Brain Images'', J. Comp. Assist. Tomogr., 22(5):827-837, 1998.

6. D. Shen and C. Davatzikos, “HAMMER: Hierarchical Attribute Matching Mechanism for Elastic Registration", IEEE Trans. on Medical Imaging, 21(11):1421-1439, 2002
Applications publications
1. S.M. Resnick, A.F. Goldszal, C. Davatzikos, S. Golski, M.A. Kraut, E.J. Metter, R.N. Bryan, and A.B. Zonderman, ``One-year age changes in MRI brain volumes in older adults'', Cerebral Cortex, 10:464-472, 2000.

2. C. Davatzikos and S.M. Resnick, ``Sex differences in anatomic measures of interhemispheric connectivity: correlations with cognition in women but not in men'', Cerebral Cortex Oct/Nov 1998;8:635-640.
Other information
atlas, functional, registration, segmentation, warping
IRIX, Linux, SunOS, UNIX
IATR listing last updated
30 May 2003